Set in a former Franciscan convent of the seventeenth century. Here you can find a little of everything from carriages to ceramics, through weapons, medals, coins, navigational instruments, sculptures, paintings, furniture and porcelain pieces, etc. Besides the museum, the monastery also houses the church of San Francisco, known as the Church of Nossa Senhora da Guia, which is a beautiful example of eighteenth-century religious architecture, boasting magnificent woodwork or ceilings, or in altarpieces and the altar . Also decorate the church sculptures and statues and unique tile panels.

This museum shows the history of wine in the region and on the island, and the importance of Verdelha caste over the centuries, also housing a room dedicated to the ethnography of the region, with many tools and objects used throughout the ages. Also houses the Wine Cellar Verdelho, the Distillery, the evidence room, the bottling room, the headquarters of the Brotherhood of the Biscuits Verdelho wine.